Given the nature of many of the androgenic and estrogenic side effects from Trenbolone, it is often difficult to minimize the risk of negative effects while still preserving the efficacy of the drug. There are certainly methods that bodybuilders use to minimize the likelihood of harmful reactions, and the most important would be only taking anabolic-androgenic steroids under the supervision of a doctor who is well-versed in steroid use.
I think that if most bodybuilders objectively consider the long-term risks versus the short-term gains, it really won’t seem worth it in the end.
Primo is available in both oral and injectable form, but it has not proven to be a successful mass building drug when taken orally because the liver usually destroys any traces of Methenolone Acetate that is ingested through the mouth. Similar to Anavar, it is mild and contains less of those steroid properties which leads to water retention or acne or any other side effects that are related to estrogen. This makes Primo a very successful drug amongst those who become easily prone to side-effects like skin problems and digestive issues.