In bodybuilding, Drostanoloneis especially popular for its properties: the drug has a diuretic effect, thereby achieving the best relief and vascularity and muscle definition. Drostanolone is valued by athletes who want to increase the density and hardness of the muscles, often used in the run-up to the competition. You can achieve excellent muscle look, due to the lipolytic effect of the drug. As practice shows, the administration rate of Drostanoloneis able to reduce body weight by 6-8% of the original, which is an excellent result (without the use of growth hormone and peptides).
Antiandrogens like spironolactone are male-specific teratogens which can feminize male fetuses due to their antiandrogen effects (see below ).    For this reason, it is recommended that antiandrogens only be used to treat women who are of reproductive age in conjunction with adequate contraception.    Oral contraceptives, which contain an estrogen and a progestin , are typically used for this purpose.  Moreover, oral contraceptives themselves are functional antiandrogens and are independently effective in the treatment of androgen-dependent skin and hair conditions, and hence can significantly augment the effectiveness of antiandrogens in the treatment of such conditions.  
In males with delayed puberty: Various dosage regimens have been used; some call for lower dosages initially with gradual increases as puberty progresses, with or without a decrease to maintenance levels. Other regimens call for higher dosage to induce pubertal changes and lower dosage for maintenance after puberty. The chronological and skeletal ages must be taken into consideration, both in determining the initial dose and in adjusting the dose. Dosage is within the range of 50 to 200 mg every 2 to 4 weeks for a limited duration, for example, 4 to 6 months. X-rays should be taken at appropriate intervals to determine the amount of bone maturation and skeletal development (see INDICATIONS AND USAGE and WARNINGS ).